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Lutein is a fat-soluble carotenoid with strong antioxidant properties. It naturally coexists with zeaxanthin in the human retina's central photoreceptor region called the macula. Since the human body cannot synthesize carotenoids on its own, it must be obtained through natural foods or supplements. Marigold (Calendula) has been identified as one of the richest sources of these compounds, and many health products extract lutein and zeaxanthin from marigold.
The functions of lutein include inhibiting free radicals, filtering blue light to reduce damage to light-sensitive cells in the eyes, and thereby protecting the retina. Moreover, research indicates that lutein can suppress inflammation-related cell signaling pathways, reduce the generation of reactive oxygen species (ROS), and regulate the immune system and inflammatory responses. This makes it beneficial in preventing conditions such as cataracts and macular degeneration.
The primary function of lutein is to protect eye tissues and slow down degeneration. Whether it can prevent eye diseases depends on factors such as age, chronic diseases, degree of myopia, lifestyle, and sunlight exposure.
Regarding claims of improving floaters and dry eyes through lutein, there is currently no substantial research confirming significant effects on these conditions.
As lutein is a fat-soluble nutrient, an excess of dietary fiber can hinder its absorption, leading to a decrease in blood carotenoid concentration. Orlistat, a weight-loss drug that inhibits lipase activity, has been shown to reduce lutein absorption. Individuals taking both Orlistat and lutein should be cautious.
Lutein is generally safe, with no evidence of long-term toxicity or teratogenicity. However, at a daily intake of 15 mg for 20 weeks, skin yellowing has been observed. The Joint FAO/WHO Expert Committee on Food Additives recommends a daily intake limit of 2 mg per kilogram, while the FDA suggests 6 mg daily to prevent macular degeneration.
Before taking lutein supplements, consider whether dietary intake is insufficient and consult a doctor to determine the appropriate dosage. Excessive intake does not provide better preventive effects and may lead to skin discoloration.
If unsure about suitability, consult a physician to determine the appropriate dosage.
In addition to supplements, lutein can be obtained through foods such as:
Steaming rather than frying these foods is recommended, as high-temperature frying may degrade lutein, reducing its effectiveness.